Ing. Radek Janča, Ph.D.

Epilepsy is a term covering brain diseases characterized by spontaneous and recurrent seizures. Effective treatment outgoes from multidisciplinary diagnoses process of neurology, electrophysiology, neuroimaging, neuropsychology, genetics, etc. Advanced diagnostic technologies bring a growing amount of data collection that required effective processing, analysis, connecting, and interpretation regarding clinical conclusions. The theme is composed of: 1) analysis of scalp and intracranial EEG for understanding the functional organization of the epileptic network, which generates and spreads seizures; 2) neuroimage processing (CT, MR, PET) for lesion detection, multimodal image visualization, and neuronavigation; and 3) multifactorial data analysis for localization of epileptogenic zones and outcome prediction. The results will help identify patients with risk of epilepsy development and more precise pre-surgery diagnostic of epilepsy surgery candidates that increase the chance of achieving seizure-free outcomes without cognitive and functional deficits after surgery.