Persons
doc. Ing. Vratislav Fabián, Ph.D.
Dissertation topics
Analysis and modeling of heat propagation through the vessel wall during endovascular laser therapy
- Branch of study: Bioengineering
- Department: Department of Physics
-
Description:
The aim of this research project is to analyze and model the process of heat propagation through the vessel wall during endovascular laser therapy, which is used in the treatment of varicose veins and other vascular diseases of the cardiovascular system. The project will focus on the physical principles of heat transfer and interactions between laser radiation and tissues. The main tasks of the project will be: 1) Creation of a detailed mathematical model that will simulate heat propagation in the vessel wall and surrounding tissues in real time during laser therapy. 2) Model validation by comparing simulation results with experimentally obtained data. 3) Analysis of model sensitivity to various laser parameters such as wavelength, power and exposure time. 4) Development of recommendations for optimizing parameters of laser therapy with the aim of maximizing treatment efficiency and minimizing damage to surrounding healthy tissues. The results of this research should contribute to a better understanding of the dynamics of heat propagation during endovascular procedures and to the development of more effective and safer treatment methods.
Non-invasive determination of the vascular wall stiffness based on pulse wave velocity
- Branch of study: Bioengineering
- Department: Department of Physics
-
Description:
Vascular wall stiffness, expressed through the aortic pulse wave velocity (PWV) is an independent cardiovascular risk factor. The aim of the thesis is to create a model to determine the stiffness of the blood vessel wall by measuring the speed of propagation of the pulse wave in various parts of the cardiovascular focusing on the various forms of primary and secondary arterial hypertension. Part of the thesis will also be a proposal of methodology of pulse wave velocity measurement, implementation of measurements on selected groups of patients with arterial hypertension and statistical evaluation against selected reference method.
Non-invasive determination of the vascular wall stiffness based on pulse wave velocity
- Branch of study: Acoustics
- Department: Department of Physics
-
Description:
Vascular wall stiffness, expressed through the aortic pulse wave velocity (PWV) is an independent cardiovascular risk factor. The aim of the thesis is to create a model to determine the stiffness of the blood vessel wall by measuring the speed of propagation of the pulse wave in various parts of the cardiovascular focusing on the various forms of primary and secondary arterial hypertension. Part of the thesis will also be a proposal of methodology of pulse wave velocity measurement, implementation of measurements on selected groups of patients with arterial hypertension and statistical evaluation against selected reference method.
